Publications by authors named "C T Soares"

The Portuguese Society of Ophthalmology and the Portuguese Society of Human Genetics developed clinical practice guidelines to streamline genetic testing for inherited retinal dystrophies (IRDs), underlining the critical role of molecular diagnosis in enhancing patient care. Genetic testing is pivotal in diagnosis, genetic counselling, prognosis and access to clinical trials, and new gene-specific therapies. These guidelines recommend genetic testing in all IRD patients and provide a detailed assessment of available testing methods, ensuring that genetic counselling is integrated into ophthalmic care.

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Article Synopsis
  • Long COVID, also known as post-acute sequelae of COVID-19 (PASC), involves lasting symptoms affecting various body systems, particularly the central nervous system (CNS) which includes issues like fatigue, brain fog, and cognitive deficits.
  • The review highlights potential mechanisms for neuro-PASC, suggesting that vascular dysfunction and disruption of the blood-brain barrier (BBB) could be key contributors to these neurological symptoms.
  • It further investigates the role of the COVID-19 spike protein interacting with brain cell receptors, which may play a significant part in the pathophysiology of long COVID symptoms.
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Temporomandibular disorders (TMD) are a public health problem that affects around 12% of the global population. The treatment is based on analgesics, non-steroidal anti-inflammatory, corticosteroids, anticonvulsants, or arthrocentesis associated with hyaluronic acid-based viscosupplementation. However, the use of hyaluronic acid alone in viscosupplementation does not seem to be enough to regulate the intra-articular inflammatory process.

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