Publications by authors named "C T Lees"

Background: Identifying fetal growth restriction and distinguishing it from a constitutionally small fetus can be challenging. The umbilical vein blood flow is a surrogate parameter of the amount of oxygen and nutrients delivered to the fetus, providing valuable insights about the function of the placenta. Nevertheless, currently, this parameter is not used in the diagnosis and management of fetal growth restriction.

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  • Stillbirth is often linked to decreased fetal movements, but current methods for tracking these movements lack accuracy and can lead to unnecessary medical interventions.
  • New technologies, including electrocardiography and accelerometry, are being developed to provide more objective and reliable quantification of fetal movements.
  • The review highlights the need for improved fetal movement monitoring solutions that allow pregnant women to maintain their daily activities while ensuring their baby's wellbeing is effectively monitored.
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  • Large-scale studies are essential to investigate the gut microbiota's complex relationships with health and disease, and tissue preservation methods need evaluation for feasibility in such research.
  • Biopsies from 20 adults with inflammatory bowel disease were preserved using three methods: flash freezing, nucleic acid preservative reagents, and formalin fixation with paraffin embedding (FFPE), with microbiota analyzed using sequencing.
  • Results showed that while preservative reagents can serve as viable alternatives to flash freezing, FFPE samples exhibited distinct community structures, highlighting the potential utility of historical samples despite differences in microbial profiles.
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Background And Aims: Over the last decade, treatment options for moderate-to-severe ulcerative colitis (UC) have expanded. However, comparative studies between these agents are limited, especially among biologic-naïve patients. We aimed to compare the persistence, effectiveness and safety of tofacitinib and vedolizumab as the first advanced treatment for patients with UC.

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Promalactis Meyrick, 1908 is one of the most diverse genera of Oecophoridae in the Old World with 407 previously accepted species. Ninety-three species of Promalactis Meyrick, 1908 (Oecophoridae) are here recognized based on the specimens in the collection of Natural History Museum, London. Among them, 33 species are described as new under the authorship of Wang: P.

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