Publications by authors named "C T Kaiser"
Transcatheter aortic valve implantation (TAVI) is recommended for treatment of high-risk aortic stenosis patients. While measuring mean transaortic valve gradient (MG) is crucial in evaluating procedural success, echocardiographic measurements often overestimate direct invasive measurements. This study aimed to examine the discordance between echocardiographic and invasive MGs in TAVI patients and assess their prognostic value on long-term outcomes.
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- The study investigates the impact of peri-procedural myocardial injury (PPMI) after transcatheter aortic valve implantation (TAVI) using the updated VARC-3 criteria compared to the previous VARC-2 criteria.
- High-sensitivity cardiac troponin T (hs-cTnT) levels were assessed pre- and post-procedure, with elevated baseline levels being significant predictors of all-cause mortality and major cardiac adverse events within one year post-TAVI.
- The findings indicate that VARC-3 criteria offered better prognostic insights regarding patient outcomes, with patients meeting VARC-3 criteria experiencing higher mortality rates than those meeting VARC-2 criteria.
Impact of new-onset atrial fibrillation in patients with ST-segment elevation myocardial infarction.
J Interv Card Electrophysiol
December 2024
Background: New-onset atrial fibrillation (NOAF) complicating ST-segment elevation myocardial infarction (STEMI) remains clinically challenging. The aim of this study was to assess the incidence of NOAF, identify risk factors for the development of atrial fibrillation (AF), and analyze the impact on patient care, therapy, and outcomes during long-term follow-up.
Methods: This retrospective single-center study reviewed consecutive patients undergoing coronary angiography (CAG) for acute STEMI between May 2015 and September 2023.
Cryo-electron tomography (cryo-ET) has become a key technique for obtaining structures of macromolecular complexes in their native environment, assessing their local organization and describing the molecular sociology of the cell. While microorganisms and adherent mammalian cells are common targets for tomography studies, appropriate sample preparation and data acquisition strategies for larger cellular assemblies such as tissues, organoids or small model organisms have only recently become sufficiently practical to allow for in-depth structural characterization of such samples in situ. These advances include tailored lift-out approaches using focused ion beam (FIB) milling, and improved data acquisition schemes.
View Article and Find Full Text PDFBackground: Risk stratification of patients with right bundle branch block (RBBB) undergoing transcatheter aortic valve implantation (TAVI) remains challenging.
Objective: This study aimed to evaluate the European Society of Cardiology (ESC) criteria for risk stratification of RBBB patients undergoing TAVI.
Methods: We retrospectively analyzed prospectively enrolled patients with preexisting RBBB undergoing TAVI between 2011 and 2023.