Publications by authors named "C T Ho"
Proton-transfer reaction time-of-flight mass spectrometry (PTR-TOF-MS), combined with electronic nose (-nose), was first used to track the change of volatile organic compounds (VOCs) in soy sauce in this study. The results showed that 163 VOCs with different mass numbers were identified. Based on the differences in VOCs, the entire fermentation cycle was divided into four stages (0D and 15D; 30D-75D; 90D; 105D-120D).
View Article and Find Full Text PDFBackground: Inadequate tumour samples often hinder molecular testing in non-small cell lung cancer (NSCLC). Plasma-based cell-free DNA (cfDNA) sequencing has shown promise in bypassing these tissue limitations. Nevertheless, pleural effusion (PE) samples may offer a richer cfDNA source for mutation detection in patients with malignant PE.
View Article and Find Full Text PDFBackground: Study aims were to assess the current state and needs of faculty to inform the design of a formal mentorship program in a large academic Department of Psychiatry.
Methods: A 57- item self-administered online survey questionnaire was distributed to all faculty members.
Results: 225 faculty members completed the survey (24%).
Article Synopsis
- Depression treatment effectiveness differs greatly among individuals, highlighting the need for objective biomarkers that can accurately predict therapy outcomes to improve treatment efficiency.
- This study used functional near-infrared spectroscopy (fNIRS) combined with clinical assessments to explore whether machine learning techniques could forecast treatment responses in patients with major depressive disorder (MDD).
- Findings revealed that changes in total hemoglobin levels in a specific brain region (dlPFC) correlated significantly with treatment response, and the fNIRS-only model demonstrated better predictive accuracy compared to a model that also included clinical data.
Background: This analysis explored real-world characteristics, treatment patterns and clinical outcomes in patients with relapsed or refractory multiple myeloma (RRMM) previously treated with lenalidomide and an anti-CD38 monoclonal antibody (mAb) and requiring subsequent treatment.
Materials And Methods: The PREAMBLE and Connect MM prospective registries of patients with multiple myeloma (MM), and the US nationwide Flatiron Health electronic health record-derived de-identified database were analysed. MM-specific treatment patterns (prior/index therapies) and outcomes (progression-free survival [PFS]/overall survival [OS]) were assessed.