Publications by authors named "C Sykes"

We describe a mortality event involving at least 44 adult American robins () that were found dead on the morning of February 25, 2023 in a residential backyard in Natchitoches Parish, Louisiana. Five carcasses were submitted for diagnostic evaluation. All five robins were in good nutritional and feather condition with no external indicators of injury or illness.

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There is increasing recognition in the field of health and social care research that community-engaged methods should include patients and the public throughout the research process. Therefore, individuals from all backgrounds should be involved in the research. We explored the public and patient engagement experience in research and how researchers and community groups can work together to make the research process more inclusive and sustainable.

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Article Synopsis
  • * The study introduces a 3D printed multipurpose prevention technology (MPT) intravaginal ring (IVR) designed to prevent HIV, HSV-2, and unintended pregnancy, utilizing advanced 3D printing techniques and biocompatible materials.
  • * The IVRs demonstrated stable drug release and safety in macaque studies, maintaining effectiveness and tolerability over a 28-day period without causing any significant inflammatory responses.
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  • Brown dwarf companions to stars help us understand planet formation processes, but some of them are more massive than expected based on their luminosities and host star ages.
  • Gliese 229 B, previously thought to be a single entity, was revealed through observations to actually be two brown dwarfs, Gliese 229 Ba and Bb, with masses of 38.1 and 34.4 Jupiter masses, respectively.
  • This discovery challenges existing theories and raises questions about the formation and occurrence of binary brown dwarfs in close orbits around stars.
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Intravaginal rings (IVRs) represent a well-established, woman-controlled and sustained vaginal drug delivery system suitable for a wide range of applications. Here, we sought to investigate the differences in etonogestrel (ENG) and ethinyl estradiol (EE) release from a 3D-printed IVR utilizing continuous liquid interface production (CLIP™) (referred to as CLIP for low drug loading and CLIP IVRs for high drug loading) and NuvaRing, a commercially available injection molded IVR. We conducted in vitro release studies in simulated vaginal fluid to compare the release of ENG and EE from CLIP IVRs and NuvaRing.

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