Prolonged hypocalcemia following denosumab therapy in metastatic hormone refractory prostate cancer.

Prostate cancer is a leading cause of cancer death, frequently associated with widespread bone metastases. We report two cases of hypocalcemia following the first dose of denosumab in metastatic hormone refractory prostate cancer, the first case requiring 26 days of intravenous calcium therapy. This is the first report of prolonged hypocalcemia following denosumab in a patient with normal renal function.

Attitudes of new mothers towards genetics and newborn screening.

Objective: To evaluate new mothers' opinions of genetics and newborn screening.

Setting: An Australian tertiary referral hospital.

Population: 232 women who delivered a liveborn infant and had received written and verbal information on newborn screening from midwifery staff during their antenatal care.

Factors affecting mothers' knowledge of genetic screening.

Objective: To evaluate mothers' knowledge of terms used in genetic counselling and their participation in Down syndrome and newborn screening.

Setting: An obstetric tertiary referral hospital in Australia.

Population: A total of 232 consecutive women delivering a liveborn baby.