Performance of computerized self-reported medical history taking and HEAR score for safe early rule-out of cardiac events in acute chest pain patients: the CLEOS-CPDS prospective cohort study.

Aims: A simplified version of the history, electrocardiogram, age, risk factors, troponin (HEART) score, excluding troponin, has been proposed to rule-out major adverse cardiac events (MACEs). Computerized history taking (CHT) provides a systematic and automated method to obtain information necessary to calculate the HEAR score. We aimed to evaluate the efficacy and diagnostic accuracy of CHT in calculating the HEAR score for predicting MACE.

Integrated Analysis of Methylome and Transcriptome Responses to Exercise Training in Children with Overweight/Obesity.

We examined the effects of a 20-week exercise intervention on whole-blood genome-wide DNA methylation signature and its association with the exercise-induced changes in gene expression profiles in boys and girls with overweight/obesity (OW/OB). Twenty-three children (10.05 ± 1.

Cumulative effects of H and P on force and power of skeletal muscle fibres from young and older adults.

The cellular causes of the age-related loss in power output and increased fatigability are unresolved. We previously observed that the depressive effects of hydrogen (H) (pH 6.2) and inorganic phosphate (P) (30 mm) did not differ in muscle fibres from young and older men.

Life cycle assessment of biochar filters for on-site wastewater treatment.

Biochar is a promising filter material for wastewater treatment. This study evaluated the environmental (climate, eutrophication, acidification) impacts of biochar filters for onsite wastewater treatment and compared them with those of a conventional sand filter. Using a parameterised life cycle assessment (LCA) approach, these three impact categories were quantified for two designs of biochar filter and a sand filter, used in normal and sensitive areas as defined by Swedish government recommendations.