Publications by authors named "C Suharti"
Introduction: Febrile neutropenia is one of the most serious complications in patients with hematological malignancies and chemotherapy. Channa striata is a freshwater fish belonging to the family Channidae. This study aims to determine whether the administration of channa striata extract can increase neutrophil count, neutrophil function and prevent incidence of febrile neutropenia in acute myeloid leukemia (AML) patients receiving chemotherapy.
View Article and Find Full Text PDFIntroduction: Breast cancer liver metastasis presents a significant challenge in clinical oncology, with limited treatment options and poor prognosis. This case series study explores the extended survival achieved in breast cancer patients with liver metastases through a combination of surgical and medical interventions.
Case Presentation: We present three cases of Javanese female patients with breast cancer (51 years old, 42 years old, and 55 years old) with liver metastases who underwent hepatic resection followed by systemic therapy.
Article Synopsis
- - Metastatic breast cancer, particularly disseminated carcinomatosis of bone marrow (DCBM), is rare and poses a serious threat to life, with a focus on managing symptoms and improving quality of life rather than finding a cure.
- - A case study is presented of a 36-year-old woman diagnosed with luminal breast cancer who experienced severe symptoms due to DCBM; she was initially treated with tamoxifen but later switched to letrozole, ribociclib, and leuprorelin due to side effects.
- - The treatment adjustment led to significant improvements in her blood markers, symptoms, and overall quality of life, suggesting that combining endocrine therapy with a CDK4/6 inhibitor could be an effective
Objective: Tumor hypoxia induces the production of Hypoxia-Inducible Factor (HIF)-1 alpha, which interacts with NF-kB, leading to cancer proliferation and metastasis. This study investigated the effect of tumor hypoxia modulation using carbogen (95% O2 and 5% CO2) and nicotinamide on reducing soluble interleukin-2 receptor (sIL-2R) levels in newly diagnosed DLBCL patients with tissue overexpression of HIF-1α ≥10%.
Material And Methods: A prospective randomized controlled clinical trial was conducted at Dr.
Introduction: Allogeneic hematopoietic cell transplantation (allo-HCT) serves as a potentially curative intervention for various hematologic disorders. However, its utility can be limited by the emergence of chronic graft-versus-host disease (cGVHD). The clinical manifestations of cGVHD result from a complex immune response characterized by the involvement of both B and T cells.
View Article and Find Full Text PDF