Publications by authors named "C Strady"
Compared Performance of the 2023 Duke-International Society for Cardiovascular Infectious Diseases, 2000 Modified Duke, and 2015 European Society of Cardiology Criteria for the Diagnosis of Infective Endocarditis in a French Multicenter Prospective Cohort.
Francois Goehringer Benoit Lalloué Christine Selton-Suty François Alla Elisabeth Botelho-Nevers Christophe Strady
Clin Infect Dis
April 2024
Article Synopsis
- The 2023 Duke-ISCVID criteria for diagnosing infective endocarditis (IE) were tested against the previous 2000 Modified Duke and 2015 ESC criteria using a large patient cohort treated for the condition.
- A total of 1194 patients were analyzed, revealing that the 2023 criteria had the highest sensitivity (97.6%) but the lowest specificity (46.0%) compared to the other criteria.
- The lower specificity in the 2023 criteria was largely due to the inclusion of patients with cardiac implanted electronic devices (CIED), highlighting the need for cautious interpretation in this group.
Article Synopsis
- The study aimed to investigate factors linked to 30-day mortality in young patients hospitalized with invasive pneumococcal disease (IPD) in France between 2013 and 2015.
- Analysis of data from two major cohort studies identified that older age, a history of malignant tumors, and meningitis were significant risk factors for increased mortality.
- The findings underscore the importance of targeted vaccination strategies for high-risk patients, particularly given that many high-mortality serotypes are included in established vaccines.