Publications by authors named "C Sternberg"
Article Synopsis
- - People of Haitian descent have faced stigma and disproportionately high rates of HIV, leading to a need for targeted research and intervention.
- - This scoping review evaluated studies on HIV prevention and treatment interventions specifically for Haitian populations, with a broad eligibility criteria and comprehensive search of eight major databases.
- - The review revealed a shortage of studies focused on Haitian populations, primarily involving women in Haiti, highlighting the necessity for community-based strategies to better address HIV-related health disparities.
Evolution of the highly successful and multidrug resistant clone ST111 in Pseudomonas aeruginosa involves serotype switching from O-antigen O4 to O12. How expression of a different O-antigen serotype alters pathogen physiology to enable global dissemination of this high-risk clone-type is not understood. Here, we engineered isogenic laboratory and clinical P.
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- The JAVELIN Bladder 100 trial demonstrated that avelumab, used as a first-line maintenance therapy, improves overall survival and progression-free survival in patients with advanced urothelial carcinoma after platinum-based chemotherapy.
- The PATRIOT-II study analyzed real-world outcomes of avelumab in 160 patients across various healthcare centers, emphasizing survival, safety, and resource use over a median follow-up of 16 months.
- Findings indicated a median progression-free survival of 5.4 months and overall survival of 24.4 months, with some patients experiencing treatment-related adverse effects, supporting the continued use of avelumab in similar patient populations.
Article Synopsis
- Darolutamide combined with androgen-deprivation therapy (ADT) and docetaxel significantly lowered the risk of death by 32.5% in the ARASENS study, indicating its effectiveness for treating metastatic hormone-sensitive prostate cancer (mHSPC).
- In the Japanese subgroup analysis of 148 patients, higher percentages of participants were older (≥75 years) and had lower body mass indexes compared to the overall study population, but the treatment showed a similar safety and efficacy profile.
- While overall survival trends were positive for darolutamide in Japanese patients, the combined treatment was well tolerated, with no new safety concerns identified, despite some patients experiencing more frequent adverse events like neutropenia.
Introduction: No consensus exists on performance standards for evaluation of generative artificial intelligence (AI) to generate medical responses. The purpose of this study was the assessment of Chat Generative Pre-trained Transformer (ChatGPT) to address medical questions in prostate cancer.
Methods: A global online survey was conducted from April to June 2023 among > 700 medical oncologists or urologists who treat patients with prostate cancer.