Publications by authors named "C Stavrianos"
Objective: Increased oxidative stress has been described in patients with Hashimoto’s thyroiditis (HT). The aim of the present study was to investigate whether high oxidative stress is further influenced by obesity and dietary habits in euthyroid women with HT.
Methods: Two hundred eighteen consecutive euthyroid women with HT were studied and separated in two groups; 102 with thyroxine replacement and 114 without.
Background: Polymorphisms of the receptor for advanced glycation end products (RAGE) gene have been studied in various autoimmune disorders, but not in Hashimoto's thyroiditis. Also, increased oxidative stress has been described in patients with Hashimoto's thyroiditis. The aim of this study was to investigate the possible role of two common RAGE polymorphisms (-429T>C, -374T>A) in Hashimoto's thyroiditis; in parallel, we studied oxidative stress levels.
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- The study focused on small medullary thyroid carcinomas (smallMTCs) that are 1.5 cm or smaller, examining how tumor size influences patient outcomes and clinical behavior over time.
- It included data from 128 patients and found that larger tumors (over 1 cm) were linked to worse prognosis, higher rates of invasion, and lower cure rates compared to smaller tumors.
- The research concluded that while tumor size is important, post-operative calcitonin levels are a stronger predictor of disease progression, indicating that higher calcitonin levels correlate with continued disease activity.
Pulpitis is a typical inflammatory disease of dental pulp, characterized by the local accumulation of inflammatory mediators, including cytokines and chemokines. In addition to serving as intercellular messengers mediating the inflammatory response, cytokines and chemokines induce the expression and stimulate the activity of molecular and cellular agents which participate actively in destructive and reparative processes in the pulp. It is the balance between these processes which eventually determines the extent of pulp inflammation and the viability of the affected tooth.
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- The study aimed to analyze the metabolic and phenotypic differences in pregnant women with one abnormal glucose value (OAV) during an oral glucose tolerance test (OGTT) compared to normal and gestational diabetes mellitus (GDM) groups.
- It involved 7,618 pregnant women, dividing the OAV group based on when hyperglycemia occurred during the OGTT: fasting, 1 hour, or 2-3 hours post-glucose intake.
- Results showed the OAV group had intermediate insulin sensitivity and secretion levels, with specific characteristics: fasting OAV exhibited higher insulin resistance and lower insulin secretion, while the 1-hour OAV indicated lower insulin responsiveness.