Publications by authors named "C Stanca"
Decision making and patient selection for isolated occlusion of the M2 segment of the middle cerebral artery is challenging, with the efficacy of treatment for such distal occlusions still controversial in recent studies, as occlusion in such small and thin vessels tends to manifest with less severe symptoms initially and hold higher surgical risks. It is even less clear which endovascular technique is more effective for this type of occlusion, with the choice usually left to the radiologist's preference. We conducted a controlled prospective study of consecutive patients presenting to Novara Hospital with an acute M2 occlusion diagnosed at the AngioCt and, following a predetermined randomization, we divided them into two treatment arms with either stent retriever aspiration (SRa) or direct aspiration (DA).
View Article and Find Full Text PDFBackground: Although it is clear that stroke is a time-dependent and age-associated disease, we still need more evidence regarding the efficacy and outcomes in elderly patients who were excluded from the first trials of mechanical thrombectomy. The aim of this study is to highlight patient characteristics, the timing of medical attention and therapy, successful recanalization, and functional outcomes in patients over 80 y/o who underwent mechanical thrombectomy at the Ospedale Maggiore della Carità di Novara (Hub) since endovascular stroke treatment was first started here.
Methods: all 122 consecutive patients over 80 y/o at admission who underwent mechanical thrombectomy between 2017 and 2022 at our Hub center were retrospectively included in our database.
Article Synopsis
- The study aimed to evaluate the eye lens doses experienced by interventional radiologists and the effectiveness of personal protective eyewear (PPE) in reducing these doses while simulating operator positions with a phantom.
- Four types of PPE were tested, revealing their dose reduction factors (DRF) and correlations between eye lens doses and whole-body doses, along with dose measurements of the brain.
- Results indicated that while all PPE showed significant DRF when used correctly, a single DRF value may not suit every situation; Kerma-Area Product (KAP) was identified as an important metric for radiation protection assessment.
Introduction: The Woven EndoBridge (WEB) device is a self-expanding intrasaccular braided-wire device for the treatment of wide-neck bifurcation aneurysms (WNBAs). Even though this device has an excellent safety profile and a low risk of rebleeding, little is known about its long-term effects.
Material And Methods: All patients treated with WEB due to ruptured WNBAs were subjected to follow-up digital subtraction angiography (DSA) at 2 and 3 years after device deployment.
Article Synopsis
- The study investigated the efficacy and safety of seladelpar, a medication for adults with primary biliary cholangitis (PBC) who are at risk of worsening disease, especially those intolerant to standard medication, ursodeoxycholic acid.
- Over 52 weeks, patients were given varying doses of seladelpar, showing significant reductions in alkaline phosphatase (ALP) levels, a marker of liver disease, particularly at higher doses (10 mg/day). Improvements were maintained over time.
- Results indicated that seladelpar was effective in improving liver function and reducing symptoms like pruritus (itching) without serious side effects, making it a promising option for PBC patients