Split Inferior Pedicle: The 1-Stage Augmentation Mastopexy for Grade 3 Ptosis.

In this article, the authors describe the 1-stage surgical technique that has been used by the senior author since 1990 for all his primary grade 2 and grade 3 augmentation-mastopexies. The article provides a safe, simple, and reproducible approach to a challenging procedure, one that tends to be the most litigious in aesthetic breast surgery. The key points of this technique are simple preoperative markings; the augmentation is performed with a true submuscular placement of smooth implants; and the mastopexy is performed with an inferior pedicle technique with unlimited skin flap undermining and no limitation of nipple elevation.

Modulation of CD36-mediated lipid accumulation and senescence by vitamin E analogs in monocytes and macrophages.

The CD36/FAT scavenger receptor/fatty acids transporter regulates cellular lipid accumulation important for inflammation, atherosclerosis, lipotoxicity, and initiation of cellular senescence. Here we compared the regulatory effects of the vitamin E analogs alpha-tocopherol (αT), alpha-tocopheryl phosphate (αTP), and αTP/βCD (a nanocarrier complex between αTP and β-cyclodextrin [βCD]) and investigated their regulatory effects on lipid accumulation, phagocytosis, and senescence in THP-1 monocytes and macrophages. Both, αTP and αTP/βCD inhibited CD36 surface exposition stronger than αT leading to more pronounced CD36-mediated events such as inhibition of DiI-labeled oxLDL uptake, phagocytosis of fluorescent Staphylococcus aureus bioparticles, and cell proliferation.

Efficacy of prophylaxis in women with sex induced cystitis.

Unlabelled: Sexual intercourse has been established as one of the most important risk factors for both isolated and recurrent uncomplicated infections of the urinary tract. Prophylactic therapy requires only a small dose of an antimicrobial agent, which is generally given at bedtime for 6 to 12 months. An alternative method is to give an antimicrobial agent for six months post-intercourse.

Sex-induced cystitis--patient burden and other epidemiological features.

Although sexual intercourse has been established as an important risk factor for uncomplicated urinary tract infection (UTI) in women, the exact the rate of recurrent UTI due to sexual intercourse and its patient burden is unknown. According to our findings, sex-induced cystitis (SIC) accounts for almost 4% of lower urinary tract infections and for 60% of the recurrent cases. Is most frequent between 23 to 27 years and affect mainly women from low and median socioeconomic groups.