Publications by authors named "C Spadini"

A short-term study was conducted to compare the effect of using poplar wood chips (PWC) instead of wheat straw (WS) litter in dairy cows. A total of 38 lactating Holstein cows (204 ± 119 days in milk, 26.9 ± 6.

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Article Synopsis
  • Azelaic Acid (AzA) is a dicarboxylic acid with anti-inflammatory and antimicrobial properties, making it effective for skin conditions like rosacea and acne.
  • * The study explores extracting AzA from whole grains using eco-friendly methods, analyzing 17 different extracts for their AzA levels and biological activities.
  • * Results showed that whole grain extracts have a broader range of activity compared to flour, with one extract (Naviglio) having higher AzA content and another (hydroalcoholic ultrasound-assisted) demonstrating better antimicrobial and antioxidant effects.
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The comprehensive identification of secondary metabolites represents a fundamental step for the assessment of bioactivities and pharmacological properties of traditional herbal drugs. (Dammer) Dammer has been described as a multipurpose remedy in different African traditional pharmacopoeias, but its phytochemical profile has not been properly investigated. Herein we report a high throughput metabolomic screening, based on ultra-high performance liquid chromatography-travelling wave ion mobility spectrometry quadrupole time-of-flight (UHPLC-TWINS-QTOF), which was performed for the first time on different plant parts.

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Klebsiella pneumoniae is the most common Klebsiella species infecting animals and is one of the causing agents of mastitis in cows. The rise of antimicrobial resistance in K. pneumoniae, particularly in strains producing extended-spectrum β-lactamases (ESBLs) and/or carbapenemases, is of concern worldwide.

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Fungal promoted infections are becoming a severe health global emergency due to drug-resistant phenomena and zoonosis. This work investigated compounds bearing acyl-/selenoureido moieties and primary/secondary sulfonamide groups as novel antifungal agents acting through organism-directed selenium toxicity and inhibition of the newly emergent therapeutic target, the Carbonic Anhydrases (CAs; EC 4.2.

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