Publications by authors named "C Soto-Fajardo"
Rheumatology (Oxford)
September 2024
Article Synopsis
- Calcium Pyrophosphate Crystal Deposition (CPPD) disease is a chronic condition affecting joints, and this study investigates the effectiveness of ultrasound (US) for diagnosing it specifically in the hip joint.
- The research involved patients over 50 years old undergoing hip replacement surgery, comparing ultrasound results against histopathology findings for detecting CPP crystals.
- The study found that US had high sensitivity (90%) and specificity (82%) for identifying CPP deposits in the hip, indicating that it is a reliable tool for diagnosing hip CPPD.
Rheumatol Int
December 2024
Article Synopsis
- Idiopathic inflammatory myopathies (IIM) and dysferlinopathies both cause muscle inflammation and weakness but have different underlying causes and implications.
- A study analyzed ultrasound differences in muscle abnormalities between 11 patients with dysferlinopathies and 11 patients with IIM, focusing on 20 muscles to see if ultrasound could aid in diagnosis.
- Results showed that specific muscle sets (biceps, quadriceps, gastrocnemius) could accurately distinguish between the two conditions, suggesting ultrasound is a valuable diagnostic tool for muscle diseases.
Article Synopsis
- * Despite his serum uric acid levels being managed, he developed new intradermal tophi, described as "miliarial-type gout," leading to surgery for his olecranon bursa due to functional limitations.
- * The case highlights persistent tophi formation despite treatment, the potential relationship between glucocorticoid use and gout symptoms, and the coexistence of urate and cholesterol crystals in olecranon bursitis, along with a novel sonographic view of the condition
Rheumatol Int
December 2023
Article Synopsis
- - The study examined the role of anti-carbamylated protein (anti-CarP) antibodies as potential biomarkers in rheumatoid arthritis (RA), focusing on their impact on disease activity and joint damage in seronegative RA (SNRA) patients.
- - Results showed that 28% of seropositive RA (SPRA) patients and only 10% of SNRA patients were positive for anti-CarP antibodies, with the anti-CarP-positive group exhibiting higher levels of C-reactive protein and disease activity scores compared to those negative for the antibodies.
- - While anti-CarP antibodies were linked to increased disease activity, they did not show a significant correlation with erosive joint damage, as assessed by musculoskeletal ultrasound,
