Publications by authors named "C Sotiropoulou"
Article Synopsis
- Acute Myeloid Leukemia (AML) is a serious illness that often needs strong treatments called chemotherapy, but sometimes these treatments don't work well enough.
- Researchers studied how certain genes related to DNA damage respond in AML cells after chemotherapy using two different medicines: Idarubicin and Cytarabine.
- They found that a gene called PPP1R15A is important for helping cells recover from stress, and when they turned off this gene, the cancer cells didn't survive as well when treated with the chemotherapy, suggesting a way to make the treatment more effective.
Colorectal cancer (CRC) is the main cause of cancer-related deaths globally, highlighting the importance of accurate biomarkers for early detection and accurate prognosis. MicroRNAs (miRNAs) have emerged as effective cancer biomarkers. The aim of this study was to investigate the prognostic potential of miR-675-5p as a molecular prognostic biomarker in CRC.
View Article and Find Full Text PDFThe first measurement of longitudinal decorrelations of harmonic flow amplitudes v_{n} for n=2-4 in Xe+Xe collisions at sqrt[s_{NN}]=5.44 TeV is obtained using 3 μb^{-1} of data with the ATLAS detector at the LHC. The decorrelation signal for v_{3} and v_{4} is found to be nearly independent of collision centrality and transverse momentum (p_{T}) requirements on final-state particles, but for v_{2} a strong centrality and p_{T} dependence is seen.
View Article and Find Full Text PDFThe utility of circular RNAs (circRNAs) as molecular biomarkers has recently emerged. However, only a handful of them have already been studied in colorectal cancer (CRC). The purpose of this study was to identify new circRNAs deriving from , a member of the BCL2 apoptosis-related family, and investigate their potential as biomarkers in CRC.
View Article and Find Full Text PDFArticle Synopsis
- The research conducted uses data from LHC Run 2, specifically analyzing proton-proton collisions at a high energy of 13 TeV to search for heavy neutral Higgs bosons using the ATLAS detector.
- The focus is on the τ^{+}τ^{-} decay channel over a mass range of 0.2-2.5 TeV, and results show that the observed data aligns well with the expected background from the standard model.
- In the context of the minimal supersymmetric standard model, certain values of tanβ are excluded at a 95% confidence level for Higgs boson masses of 1.0 and 1.5 TeV, indicating restricted parameter space for this theoretical model.