Publications by authors named "C Soon"

Cardiovascular diseases are a major cause of mortality worldwide. Long-term monitoring of nighttime heart rate (HR) and heart rate variability (HRV) may be useful in identifying latent cardiovascular risk. The Oura Ring has shown excellent correlation only with ECG-derived HR, but not HRV.

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Polyfunctional T cells programmed to perform activities such as degranulation of lytic enzymes and simultaneous production of multiple cytokines are associated with more effective control of viral infections. Immune responses to recombinant adeno-associated virus (rAAV) vector delivery systems can critically influence therapeutic efficacy and safety of gene therapy. However, knowledge of polyfunctional T cells in anti-AAV immune responses is scarce.

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Since the Tactical Games Model (TGM) was adopted and popularised by Oslin, Griffin, and Mitchell, research interest in this model has surged, increasing its application in teaching and research. However, much-existing research is fragmented and lacks a comprehensive review. This systematic review aims to fill that gap by thoroughly analysing the literature on TGM within the context of physical education, highlighting current trends and developments.

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  • Extended work hours and night shifts in healthcare can negatively impact physicians' sleep, well-being, and patient care, suggesting that alternative work schedules with shorter hours may help alleviate these problems.
  • An observational study tracked interns at a Singapore hospital for 8 weeks to compare the effects of irregular, extended shifts versus more regular, restricted-hour schedules on sleep, well-being, and cognitive performance.
  • Results indicated that participant well-being and sleep patterns varied significantly between those on irregular call schedules and those on a float schedule, highlighting the potential benefits of more predictable work hours for healthcare professionals.
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  • * Research indicates that inhibiting two specific enzymes, PDE1B and PDE10A, could help address various symptoms of schizophrenia, leading to a study on dual inhibitors using advanced modeling techniques.
  • * The study identified a promising compound, UNPD167314, through virtual screening, which showed strong interactions with the target receptors and led to the design of 35 new inhibitors, with four showing great potential for further development.
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