Medical Kitchen: Transdisciplinary Clinical Skills Training.

Background: Medical Kitchen is an innovative transdisciplinary simulation aimed at helping 2nd-year medical students at Imperial College London transition from declarative to procedural knowledge acquisition and prepare them for learning clinical skills, grounded in established psychomotor skills development theories, including Kovacs' definitions and the Fitts and Posner's model.

Approach: It employs a transdisciplinary simulation approach that blends professional gastronomy with medical training. Designed initially in response to the 2020 Covid-19 pandemic, the course offers a scalable and replicable model that includes mechanisms for peer feedback and reflective exercises.

Imaging the Female Urethra: US and MRI in Cystic and Solid Pathologic Conditions.

The female urethra can be affected by numerous pathologic conditions, many of which are infrequent and often underdiagnosed, particularly before the introduction of MRI. Diagnosing urethral pathologic conditions is challenging due to ambiguous signs and symptoms, nonspecific physical examinations, atypical presentations (such as benign conditions mimicking malignant disorders), and large lesions. Various imaging techniques, including transperineal or transvaginal US and MRI, are essential for accurate anatomic and tissue characterization.

Evaluating Pediatric NAFLD with Controlled Attenuation Parameter: A Comprehensive Narrative Review.

Non-alcoholic fatty liver disease (NAFLD) in the pediatric population has emerged as a significant health concern due to its alarming rise in prevalence. In children, the characteristics of the disease differ from those seen in adults. NAFLD may progress to more severe liver disease in children compared to adults with similar profiles.

Prevalence and severity of anxiety, stress, and depression in long COVID among adults in Barcelona.

Background: The COVID-19 pandemic's long-term mental health implications are increasingly concerning, especially among patients suffering post-acute sequelae of SARS-CoV-2 infection: Long COVID (LC) patients.

Aim: This study explores the presence and distribution of anxiety, depression, and stress in LC individuals with cognitive complaints in northern Barcelona (Spain).

Design & Settings: This cross-sectional study involved 155 diagnosed LC individuals from the "Aliança ProHEpiC-19 Cognitiu (APC)" project.

Artificial enforcement of the unfolded protein response reduces disease features in multiple preclinical models of ALS/FTD.

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are part of a spectrum of diseases that share several causative genes, resulting in a combinatory of motor and cognitive symptoms and abnormal protein aggregation. Multiple unbiased studies have revealed that proteostasis impairment at the level of the endoplasmic reticulum (ER) is a transversal pathogenic feature of ALS/FTD. The transcription factor XBP1s is a master regulator of the unfolded protein response (UPR), the main adaptive pathway to cope with ER stress.