Publications by authors named "C Silversides"

Background: Rheumatic heart disease (RHD) remains as 1 of the major contributors to indirect pregnancy-related mortality and morbidity worldwide and disproportionately affects marginalized populations.

Objectives: In this scoping review, the authors sought to explore the socioeconomic, cultural, and health care access-related causes of global disparities in outcomes of pregnancy among individuals with RHD.

Methods: We performed a literature search of all studies published between January 1, 1990, and January 1, 2022, that investigated causes for disparate outcomes in pregnant individuals with RHD.

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The use of assisted reproductive technology (ART) is growing, both to assist individuals with infertility and for fertility preservation. Individuals with cardiovascular disease (CVD), or risk factors for CVD, are increasingly using ART. Thus, knowing how to care for patients undergoing ART is important for the cardiovascular clinician.

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Article Synopsis
  • - The study evaluated the survival rates and need for re-operation in children who had surgery for transposition of great arteries (TGA) from 1990 to 2019, finding a strong 30-year survival rate of 92% and a low in-hospital death rate of 3.8%.
  • - Most patients (94%) underwent arterial switch operations, with 82% being free from cardiac re-operations 30 years post-surgery. Re-operation rates were highest in the first 2 years, then decreased for 18 years, followed by an increase after 20 years.
  • - Late complications were noted, particularly a concerning rise in neo-aortic valve and root re-operations after 17 years,
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  • The study investigates the effectiveness of intracardiac echocardiography (ICE) in improving catheter ablation outcomes for ventricular tachycardia (VT) in adults with repaired tetralogy of Fallot (TOF).
  • Results showed that ICE significantly enhanced isthmus localization and ablation success rates, but did not improve long-term freedom from VT or affect overall procedural times and complications.
  • The conclusion emphasizes that while ICE is beneficial for tailored ablation based on individual anatomy, it does not lead to better long-term patient outcomes for VT in the context of repaired TOF.
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Article Synopsis
  • Rastelli surgery is performed to correct congenital heart defects, but late-onset cardiac arrhythmias are a notable complication, and there's limited data on their occurrence after this surgery.
  • In a study of 55 patients followed for over 24 years, 38.4% experienced tachyarrhythmias, with older age at surgery linked to a higher risk; 21.8% had bradyarrhythmias, and some required catheter ablation.
  • The results indicate that arrhythmia prevalence is significant and increases with age post-surgery, emphasizing the need for long-term monitoring in patients who underwent Rastelli surgery.
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