Publications by authors named "C Sifer"
Article Synopsis
- The study investigates whether breast cancer prognostic factors affect ovarian reserve and response during fertility preservation treatments in women with breast cancer.
- The research involved analyzing data from 352 women who underwent ovarian stimulation, measuring key fertility indicators like serum anti-Müllerian hormone (AMH) levels and antral follicle counts.
- Findings indicate that while ovarian reserve markers like antral follicle count impact the number of mature oocytes retrieved, breast cancer prognostic factors do not significantly influence ovarian stimulation outcomes, suggesting these factors should not affect fertility-preservation strategies.
Objective: To study the fertility outcomes of women who tried to conceive after breast cancer (BC) treatment and fertility preservation.
Design: Retrospective observational, bicentric cohort study.
Setting: University hospital.
Study Question: What are the potential risk factors for poor oocyte recuperation rate (ORR) and oocyte immaturity after GnRH agonist (GnRHa) ovulation triggering?
Summary Answer: Lower ovarian reserve and LH levels after GnRHa triggering are risk factors of poor ORR. Higher BMI and anti-Müllerian hormone (AMH) levels are risk factors of poor oocyte maturation rate (OMR).
What Is Known Already: The use of GnRHa to trigger ovulation is increasing.
Objective: To determine whether oxygen (O) tension (20% vs. 5%) has an impact on oocyte maturation rates and morphology during in vitro maturation (IVM).
Design: A prospective, observational, monocentric, sibling-oocyte study.