Publications by authors named "C Shimada"

Article Synopsis
  • Hydrogen boride (HB) nanosheets are considered lightweight and safe hydrogen carriers due to their high hydrogen density (8.5 wt %) and ability to release hydrogen when exposed to light.* -
  • The study introduces dye-modified HB nanosheets that can generate hydrogen using visible light (over 470 nm), eliminating the need for heat, by allowing electron transfer from excited dye molecules.* -
  • While the hydrogen production decreases over time due to dye oxidation, enhancing the process with agents like iodine ions and formic acid can sustain hydrogen generation from these nanosheets for longer periods.*
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Transcriptional activation, based on Clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9 (Cas9) and known as CRISPR activation (CRISPRa), is a specific and safe tool to upregulate endogenous genes. Therefore, CRISPRa is valuable not only for analysis of molecular mechanisms of cellular events, but also for treatment of various diseases. Regulating autophagy has been proposed to enhance effects of some therapies.

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Aim: This study examines patterns and predictors of site-specific recurrence to explore the causes of local recurrence of cervical cancer.

Methods: Radical hysterectomy was performed in 121 patients (stage IB-IIB). Nerve-sparing was performed whenever possible.

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Context: A conceptual framework for advance care planning is lacking in societies like Japan's valuing family-centered decision-making.

Objectives: A consensus definition of advance care planning with action guideline adapted to Japanese society.

Methods: We conducted a multidisciplinary modified Delphi study 2020-2022.

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