Publications by authors named "C Sherman"
Background/aim: Scapular osteosarcoma is a rare malignancy, and the understanding of its optimal treatment strategies and long-term outcomes remains limited. The purpose of the current study was to evaluate our institutional experience.
Patients And Methods: We reviewed 14 patients (8 females, 5 males; mean age 44±17 years) treated for scapular osteosarcoma from 1985 to 2022.
Background: Change in the oxygen consumption (VO) at the ventilatory anaerobic threshold (VAT) is an important outcome in research studies of children with congenital heart disease (CHD). The range of values reported by different raters for any given VAT is needed to contextualize a change in VAT in intervention studies.
Methods: Sixty maximal cardiopulmonary exercise tests (CPET) for CHD patients 8-21 years old were independently reviewed by six exercise physiologists and four pediatric cardiologists.
A 77-year-old woman presented with metastatic urothelial carcinoma as an elbow mass. To our knowledge, this is only the third reported case of urothelial carcinoma metastasizing to the upper extremity. The presence of metastatic disease at the time of diagnosis of urothelial carcinoma is rare, with metastases to the upper extremities even less common.
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- Assessing ocean biodiversity is challenging, with limited global indicators highlighting overfishing as a major threat, impacting shark and ray populations.
- Analysis of 1199 species shows their populations have declined by 50% since 1970, with a 19% increase in extinction risk, particularly in regions with high coastal human populations.
- Sustainable fishing practices and restrictions on threatened species can help prevent further biodiversity loss and maintain ecological balance in marine environments.
Article Synopsis
- - Loss-of-function studies reveal that T cell factor-1 (TCF1) is crucial for T cell development in the thymus, and its expression is regulated by E box DNA binding proteins independently of Notch signaling.
- - Systematic analysis of five E protein binding elements (EPE1-5) shows that EPE3 is vital for αβ T cell development, while EPE1, 3, and 5 are important for γδ T cell maturation and fate decisions.
- - The balanced expression of TCF1, influenced by specific EPEs, is essential for generating the appropriate number of T cells in the thymus.