Electrochemiluminescence in Microfluidic Channels: Influence of Mass Transport on the Tris(2,2'-bipyridyl)ruthenium(II)/Tripropylamine System at Semitransparent Electrodes.

Mass transport in laminar flow can improve the electrochemiluminescence (ECL) performance at the microchannel electrodes, depending on the device geometry and operating regimes. The known Ru(bpy)/tripropylamine (TPA) system was selected and studied in continuous microfluidics on semitransparent platinum electrodes. With this electrode material, ECL is mainly generated via a catalytic pathway.

Surgery and Prophylaxis with Susoctocog-Alfa in Acquired Hemophilia: Case Series and Literature Review.

Background: Acquired hemophilia A (AHA) is a rare bleeding disease due to autoantibodies directed against clotting factor VIII (FVIII). Treatment of AHA consists of inhibitor eradication with immunosuppressive therapy (IST) and prompt control of bleeding obtained with bypassing agents or recombinant porcine FVIII (rpFVIII). The latter has recently been licensed for management of acute bleeding in AHA.

Impact of COVID-19 Infection, Vaccination, and Serological Response in Immune Thrombocytopenic Purpura Patients: A Single-Center Global Analysis.

Both SARS-CoV-2 infection and vaccination have raised concern in immune-mediated diseases, including immune thrombocytopenic purpura (ITP) considering risk of de novo ITP development and ITP recurrence. Here, we report on data from a single-center retrospective-prospective collection aiming to evaluate platelet (plt) dynamics in patients (pts) with chronic ITP after COVID-19 infection (before and after vaccination) and after the first, second and third vaccine doses. Furthermore, we analyzed the serological response after the first two doses of COVID-19 vaccination.

Environmental analysis of the eutrophication and spread of aquatic macrophytes in a tropical reservoir: a case study in Brazil.

Land use changes threaten the maintenance of water quality and challenge the management of tropical reservoirs. In particular, eutrophication alters several ecosystem functions and services, compromising multiple uses of water. For example, in the Lajeado Reservoir (Araraquara, São Paulo, Brazil), aquatic macrophytes rapidly spread and occupied more than 90% of the system's surface area (from 2016 to 2019).