[Almitrine per os in the therapy of chronic obstructive bronchopneumopathies].

A double-blind study was conducted to evaluate the effects of almitrine, administered orally as 3.5 mg/kg/day for one month, when compared with placebo in 20 patients with chronic obstructive pneumopathies from smoking, currently in the stage of chronic hypercapnic respiratory insufficiency. Clinical improvement was obtained, with a reduction in dyspnea and a more comfortable respiration.

[Evaluation of total serum complement by radial immunohemolysis in allergic asthma].

The role of the complement system in human allergic asthma has been studied by serum complement evaluation by radial immuno-hemolysis. Various groups were tested: 50 normal subjects, 49 allergic patients, 6 pollen sensible patients during and after pollinic season. Complement was evaluated during and after allergen challenge (11 patients).

Hereditary angio-oedema and C3 nephritic factor--HL-A study.

In one family of twenty-four members hereditary angio-oedema was present in the family for six generations. The protein C1 esterase inactivator found in nine patients proved to be non-active in a functional test. Another anomaly found in the complementary system was labelled C3 nephritic factor without any renal, or other clinical symptoms.