Publications by authors named "C Secombes"
Article Synopsis
- The study investigates the colony-stimulating factor-1 receptor (MCSFR) in rainbow trout, identifying four gene variants, including two previously unrecognized, and explores their expression levels in various tissues.
- The protein structure of MCSFRs includes five immunoglobulin-like domains and suggests a conserved function across species.
- Following infection with Yersinia ruckeri, different MCSFR paralogues exhibit unique expression patterns, showing complex regulatory mechanisms influenced by various stimuli, enhancing the understanding of immune responses in fish.
Article Synopsis
- Lyme Borreliosis (LB), or Lyme disease, is increasingly concerning due to its severe health risks from untreated cases, often diagnosed too late with current tests having low sensitivity.
- A new diagnostic test, the Epitogen Lyme Detect IgG ELISA, was validated in this study using 220 serum samples to assess sensitivity and specificity against the standard LIAISON Borrelia IgG test.
- The Epitogen test showed comparable performance for late stages of LB and significantly higher sensitivity for early suspected cases, indicating it could improve early and accurate diagnosis of Lyme disease.
Introduction: Little is known about the proteomic changes at the portals of entry in rainbow trout after infection with the myxozoan parasites, , and . Whirling disease (WD) is a severe disease of salmonids, caused by the myxosporean , while, proliferative kidney disease (PKD) is caused by , which instead belongs to the class Malacosporea. Climate change is providing more suitable conditions for myxozoan parasites lifecycle, posing a high risk to salmonid aquaculture and contributing to the decline of wild trout populations in North America and Europe.
View Article and Find Full Text PDFStreptococcosis, an emerging infectious disease caused by Streptococcus agalactiae, has had adverse effects on farmed tilapia. Several vaccines have been developed to prevent this disease and induce a specific immune response against S. agalactiae infection.
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