Publications by authors named "C Scott Little"
Article Synopsis
- Charcoal rot, caused by the fungus Macrophomina phaseolina, is a significant threat to soybean crops, particularly in the Midwest USA, making resistance breeding challenging due to the complex interactions at the molecular level.
- A study found that pre-treating soybeans with L-ascorbic acid (LAA) before the fungus infection reduced the severity of the disease by influencing gene expression related to stress responses and photosynthesis.
- The research identified that while many genes were down-regulated during the fungus attack, LAA treatment could boost certain protective genes, highlighting the intricate relationship between plant defense mechanisms and the pathogen's impact.
Article Synopsis
- The movement and distribution of essential elements in nature significantly affect the structure and function of biological communities, but our understanding of these distributions, especially for bioavailable elements, is still limited.
- The authors propose a quantitative framework that combines distribution models and spatial analysis techniques to study how these elements are distributed over different areas.
- This research provides insight into the relationships among elements in ecosystems, which can be measured and used to identify key factors that influence community and ecosystem dynamics.
Antimicrobial drug pricing.
Commun Med (Lond)
October 2024
Despite the constant development of antimicrobial resistance (AMR), few new antimicrobials are currently becoming available clinically. Alternative approaches, such as different mechanisms to fund their use, are being explored to encourage development of new antimicrobials.
View Article and Find Full Text PDFIntroduction: Limited research has explored immunosuppressant medication adherence over time in pediatric transplant patients, who often struggle with posttransplant regimen adherence, resulting in poor outcomes.
Methods: This study investigated the longitudinal growth in immunosuppressive medication levels following transplantation. Medication level variability index (MLVI) scores from tacrolimus blood levels of pediatric organ transplant recipients at a major medical center were analyzed.
Article Synopsis
- Evidence suggests that returning to play after a concussion increases the risk of musculoskeletal injuries due to undetected neuromuscular control deficits, highlighting the potential benefits of rehabilitation programs.
- A feasibility trial tested an 8-week virtual neuromuscular training (NMT) program via a smartphone app, where participants completed three self-guided workouts per week incorporating various exercises.
- Out of 20 enrolled participants, 15 completed the program with a retention rate of 75%, and adherence was moderate at 57.2%, with time constraints reported as a significant barrier to completion.