Publications by authors named "C Scolfaro"

Article Synopsis
  • The study investigates meningitis-retention syndrome (MRS), focusing on its clinical and radiological features, treatment options, and urinary outcomes to better understand the syndrome and the role of corticosteroids.
  • A new case of MRS was presented alongside a review of 28 previous cases, revealing that MRS typically occurs with aseptic meningitis and urinary retention, with a mean interval of about 6.4 days between symptoms.
  • Findings suggest MRS is self-limited, often without pathological findings on neurophysiological studies, and corticosteroids, antibiotics, and antivirals have not shown effectiveness in altering the syndrome's course.
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Malaria is not endemic in Italy, however every year about 600-700 imported cases are detected in people born or living in Italy who return from a stay in their country of origin (visiting friends and relatives - VFR). Children account for 20% of this population and they have an higher risk of severe disease. Socio-economic problems and deficiencies in the doctor-patient relationship often lead to a lack of awareness of the importance of prophylaxis, making the category of VFRs at increased risk of disease.

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Children with the new coronavirus disease 2019 (COVID-19) have milder symptoms and a better prognosis than adult patients. Several investigations assessed type I, II, and III interferon (IFN) signatures in SARS-CoV-2 infected adults, however no data are available for pediatric patients. TRIM28 and SETDB1 regulate the transcription of multiple genes involved in the immune response as well as of human endogenous retroviruses (HERVs).

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