Publications by authors named "C Schoen"
Background: Accuracy of genomic prediction depends on the heritability of the trait, the size of the training set, the relationship of the candidates to the training set, and the , where is the number of QTL and is the number of independently segregating chromosomal segments. Due to LD, the number of independently segregating QTL (effective QTL) can be lower than . In this paper, we show that is inversely associated with the trait-specific genomic relationship of a candidate to the training set.
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- The study examined antibiotic treatment practices and clinical outcomes in 1,402 hospitalized children with pediatric parapneumonic effusion/pleural empyema from 2010 to 2018 in Germany.
- Although aminopenicillin/beta-lactamase inhibitors and cefuroxime were commonly used, the study found no significant difference in clinical severity or outcomes between these treatments, regardless of whether they were used alone or in combination.
- The findings indicated a trend of antibiotic overtreatment, with a low percentage of patients switching to narrow-spectrum antibiotics despite the identification of specific bacterial pathogens.
Introduction: To objectify self-reported sleep disorders in individuals with post-COVID-syndrome (PCS), we aimed to investigate the prevalence and nature of sleep disturbances by polysomnography (PSG) in PCS compared to healthy individuals.
Methods: People with PCS (n = 21) and healthy controls (CON, n = 10) were included in this prospective trial. At baseline, clinical and social anamnesis, lung function, 1 min sit-to-stand test (STST) and Pittsburgh Sleep Quality Index (PSQI) were assessed.
The ability of the centrifugal Lab-on-a-Disc (LoaD) platform to closely mimic the "on bench" liquid handling steps (laboratory unit operations (LUOs)) such as metering, mixing, and aliquoting supports on-disc automation of bioassay without the need for extensive biological optimization. Thus, well-established bioassays, normally conducted manually using pipettes or using liquid handling robots, can be relatively easily automated in self-contained microfluidic chips suitable for use in point-of-care or point-of-use settings. The LoaD's ease of automation is largely dependent on valves that can control liquid movement on the rotating disc.
View Article and Find Full Text PDFInduction of labor versus expectant management in patients with idiopathic polyhydramnios.
Eur J Obstet Gynecol Reprod Biol
January 2024
Objective: To evaluate whether induction of labor is associated with lower risk of cesarean section compared to expectant management in patients with isolated polyhydramnios.
Study Design: This is a single-center, retrospective cohort study of patients with pregnancies complicated by idiopathic polyhydramnios, documented between 34 and 38 weeks gestation, who were delivered between July 2012 and February 2020. The primary outcome was cesarean delivery.