Publications by authors named "C Schiano"
Article Synopsis
- RNA modifications, known as "epitranscriptome" alterations, are crucial in regulating various cellular networks and are particularly relevant in cardiovascular diseases, especially during the progression of atherosclerosis.
- Key RNA modifications include m6A, m5C, m1A, m7G, Ψ, and A-to-I editing, with ongoing research focused on targeting enzymes related to these modifications, like METTL3 and FTO, using small molecule inhibitors or activators.
- Identifying drug candidates for RNA epitranscriptome modulation presents a major challenge, but promising findings include Panax notoginseng and rhein, which may enhance mRNA m6A levels and provide insights into developing biomarkers for better prediction
Quantum interference is a central resource in many quantum-enhanced tasks, from computation to communication. While usually occurring between identical photons, it can also be enabled by performing projective measurements that render the photons indistinguishable, a process known as quantum erasing. Structured light forms another hallmark of photonics, achieved by manipulating the degrees of freedom of light, and enables a multitude of applications in both classical and quantum regimes.
View Article and Find Full Text PDFFamilial dilated cardiomyopathy (DCM) is among the leading indications for heart transplantation. DCM alters the transcriptomic profile. The alteration or activation/silencing of physiologically operating transcripts may explain the onset and progression of this pathological state.
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