Publications by authors named "C Scardino"

Background: The long-term cardiovascular (CV) outcomes of COVID-19 have not been fully explored.

Methods: This was an international, multicenter, retrospective cohort study conducted between February and December 2020. Consecutive patients ≥18 years who underwent a real-time reverse transcriptase-polymerase chain reaction (RT-PCR) for SARS-CoV2 were included.

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Article Synopsis
  • The study explored the effectiveness of emergency coronary angiography (CAG) and percutaneous coronary intervention (PCI) in improving survival and neurological outcomes for patients who experienced out-of-hospital cardiac arrest (OHCA) without STEMI.
  • Researchers conducted a randomized trial with 69 OHCA survivors, assigning them to either immediate CAG or deferred CAG, focusing on in-hospital survival and major adverse cardiac events as primary endpoints.
  • Results showed no significant difference in survival rates between the immediate and delayed CAG groups, concluding that immediate intervention did not offer benefits in terms of survival without neurological impairment.
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  • Sudden cardiac death (SCD) significantly affects healthcare due to its cardiological and neurological complications, especially among the elderly, leading to more admissions in intensive care.
  • A study analyzing SCD patients from five hospitals found that patients aged 80 and older received less aggressive treatments, like new antiplatelet agents and coronary angiography, compared to younger patients.
  • While older age was linked to worse survival rates, it did not correlate with poorer neurological outcomes; instead, factors like rhythm type and time to CPR were more predictive of outcomes regardless of age.
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The aim of this observational study was to assess long-term prognosis of a contemporary octogenarian population admitted to an Intensive Cardiac Care Unit with acute myocardial infarction (MI), and the prognostic value of two simple biomarkers obtained at admission: glucose blood level (ABG) and estimated glomerular filtration rate (eGFR). A total of 293 consecutive patients were included (202 with ST elevation MI and 91 with non-ST elevation MI) with median age 83.9 years, 172 (58.

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Article Synopsis
  • Severe mitral regurgitation (MR) after acute myocardial infarction (MI) is linked to high mortality, prompting a study of outcomes for different treatment methods, including conservative, surgical, and percutaneous interventions.
  • A total of 471 patients were analyzed, showing that early intervention (either surgical or percutaneous) led to lower in-hospital and one-year mortality rates compared to conservative treatment, despite patients in intervention groups being in worse clinical condition.
  • While immediate success rates were similar for surgical mitral valve repair and percutaneous methods, the surgical approach had higher in-hospital and one-year mortality rates, suggesting percutaneous repair may be a safer alternative to surgery.
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