Publications by authors named "C Scandellari"

Background: In the general population, maternal SARS-CoV-2 infection during pregnancy is associated with worse maternal outcomes; however, only one study so far has evaluated COVID-19 clinical outcomes in pregnant and postpartum women with multiple sclerosis, showing no higher risk for poor COVID-19 outcomes in these patients.

Objective: In this multicenter study, we aimed to evaluate COVID-19 clinical outcomes in pregnant patients with multiple sclerosis.

Methods: We recruited 85 pregnant patients with multiple sclerosis who contracted COVID-19 after conception and were prospectively followed-up in Italian and Turkish Centers, in the period 2020-2022.

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Article Synopsis
  • - The study aimed to investigate the effects of long-term exposure to air pollutants (PM2.5, PM10, and NO2) on the severity of Covid-19 pneumonia specifically in patients with Multiple Sclerosis (MS), building on previous research that only considered PM2.5.
  • - Researchers conducted a case-control study with 491 MS patients, utilizing statistical methods such as logistic regression and weighted quantile sum regression to analyze the relationship between pollutant exposure and the likelihood of developing Covid-19 pneumonia.
  • - Results indicated that higher levels of PM2.5, PM10, and NO2 were significantly linked to increased chances of Covid-19 pneumonia, with NO2 and PM2.5 identified as the most
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Background And Purpose: Clinical outcomes of multiple sclerosis (MS) patients affected by coronavirus disease 2019 (COVID-19) have been thoroughly investigated, but a further analysis on main signs and symptoms and their risk factors still needs attention. The objective of this study was to group together and describe based on similarity the most common signs and symptoms of COVID-19 in MS patients and identify all factors associated with their manifestation.

Method: Logistic and linear regression models were run to recognize factors associated with each pooled group of symptoms and their total number.

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Background: Many risk factors for the development of severe forms of Covid-19 have been identified, some applying to the general population and others specific to Multiple Sclerosis (MS) patients. However, a score for quantifying the individual risk of severe Covid-19 in patients with MS is not available. The aim of this study was to construct such score and to evaluate its performance.

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Background And Aim: Limited data are available in clinical settings on the pharmacokinetics of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). We investigated the use of cannabis-based products in neurological practice, monitoring patients' steady-state cannabinoids (CBs) plasma concentrations matched with different preparations.

Methods: This was a prospective, single-center, observational study.

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