Publications by authors named "C Sarlo"
Article Synopsis
- Bullous pemphigoid (BP) is a rare blistering skin disease that may signal underlying cancers, particularly hematological malignancies like acute myeloid leukemia (AML).
- A 28-year-old male patient with both BP and de novo AML was treated using a combination of immunosuppressive therapy and chemotherapy to effectively address both conditions.
- After aggressive treatment, the patient achieved full remission from AML and complete resolution of BP, along with normalized BP180 antibody levels after receiving an autologous stem cell transplant.
Health-related quality of life (HRQoL) is an important goal of therapy for patients with myelodysplastic syndromes (MDS); however, little is known about HRQoL of these patients at clinical presentation. We report HRQoL profile of newly diagnosed patients with MDS across both the the International Prognostic Scoring System (IPSS) and IPSS-Revised (IPSS-R) classifications, stratified by sex and age group categories, aiming to also establish European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core30 (EORTC QLQ-C30) reference values for these patients. Analysis was based on 927 patients with a median age of 73.
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- Hairy cell leukemia (HCL) is a rare cancer that has a high success rate when treated with cladribine (2CDA), though some patients may experience relapse later on.
- A study analyzed data from 513 HCL patients treated with 2CDA between 1991 and 2019, showing an overall response rate of 91.8% and a median follow-up of 6.83 years, indicating long-term effectiveness of the treatment.
- The study found that factors like hemoglobin levels and spleen normalization were linked to better treatment outcomes, with a major takeaway that about 80% of patients are expected to survive 15 years post-diagnosis.