Publications by authors named "C Santucci"
Article Synopsis
- * Analysis of WHO mortality data revealed that colorectal cancer mortality rates have increased in several countries, particularly in the UK and Mexico, despite a general decline in total cancer mortality across most nations.
- * The findings underscore the importance of addressing the obesity epidemic and enhancing cancer surveillance strategies aimed at younger populations to combat the rising mortality from colorectal cancer.
Background: Gastric cancer (GC) incidence has been decreasing over the last decades; however, there are uncertainties in trends and proportional distribution of the diffuse type.
Methods: GC incidence data were extracted from the population-based Friuli Venezia Giulia Cancer Registry. GC types (diffuse vs.
Parents' age and total fertility rate in selected high-income countries from Europe and North America, 1990-2020.
Eur J Obstet Gynecol Reprod Biol
August 2024
Article Synopsis
- * Findings reveal that mean maternal age at birth is rising, with Italy and Spain having the highest ages (32.2 and 32.3 years, respectively), while the USA has the lowest at 28.8 years.
- * Fertility rates show significant variation, with Sweden and the USA reaching about two children per woman, while Italy and Spain remain below 1.5 children, highlighting changes in reproductive behaviors over time.
Background: The therapeutic scenario in multiple sclerosis (MS) has evolved over recent years with the progressive introduction of new drugs focused to better balance efficacy, safety and management requirements. The objective of this study was to examine the prescribing patterns of disease-modifying therapies (DMT) over time and across different geographic areas, and the latency between disease onset, first Register center visit, disease diagnosis, and the start of treatment in a large cohort of persons with MS from the Italian Multiple Sclerosis and Related Disorders Register.
Methods: Up to 2022, the Register collected data from 124 centers on more than 78,000 persons, of whom 56,872 received at least one DMT prescription.
Epidermolysis bullosa (EB) is an umbrella term for a group of rare inherited skin disorders characterised by mucocutaneous fragility. Patients suffer from blisters and chronic wounds that arise spontaneously or following minor mechanical trauma, often resulting in inflammation, scarring and fibrosis due to poor healing. The recessive form of dystrophic EB (RDEB) has a particularly severe phenotype and is caused by mutations in the COL7A1 gene, encoding the collagen VII protein, which is responsible for adhering the epidermis and dermis together.
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