Publications by authors named "C Santos-Buelga"

Phenolic compounds present in plants and foods are receiving increasing attention for their bioactive and sensory properties, accompanied by consumers' interest in products with health benefits derived from natural rather than artificial sources. This, together with the sustainable development goals for the 21st century, has driven the development of green extraction techniques that allow obtaining these compounds with the safety and quality required to be applied in the food, cosmetic and pharmaceutical industries. Green extraction of natural products involves practices aiming at reducing the environmental impact of the preparation processes, based on using natural or less-polluting solvents, lower energetic requirements and shorter extraction times, while providing greater efficiency in the recovery of target compounds.

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Alzheimer's disease (AD), a major neurodegenerative disorder, is characterized by the progressive accumulation of amyloid-β (Aβ) plaques, leading to cognitive decline. Despite the existing treatments, their limited efficacy highlights the urgent need for novel therapeutic strategies. The present study investigates the neuroprotective effects of a grape seed polyphenol extract (GSPE) on transgenic models specifically expressing human Aβ proteins.

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Article Synopsis
  • The Andean blackberry, or "Mora de Castilla," is a high-altitude fruit known for its rich antioxidant phytochemicals, particularly anthocyanins, although the impact of altitude on its chemical properties remains uncertain.
  • This research involved collecting blackberry fruits from various altitudes and developmental stages in Ecuador, utilizing methods like hydroalcoholic extraction and high-performance liquid chromatography to analyze phytochemical content and antioxidant activity.
  • Results showed that unripe blackberries mainly contain flavonols like quercetin, while ripe blackberries have higher levels of anthocyanins, indicating a shift in dominant compounds as the fruit ripens, with polyphenols initially driving antioxidant capacity and anthocyanins increasing in prominence later on
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This research investigated the effects of hydroponic cultivation with enriched concentrations of magnesium (+Mg), manganese (+Mn), a combination of +Mg and +Mn, or decreased concentrations of these minerals (control) on the nutritional, chemical, and bioactive attributes of purple and green basil. While Mn significantly increased the growth of purple basil and affected the composition of essential oil and mineral accumulation, plants treated with Mg showed alterations in nutrient absorption. Protein values were lower, indicating suboptimal protein synthesis, but significant increases were observed in fat, ash, and carbohydrates, suggesting a more nutrient-rich composition due to hydroponic cultivation.

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Blue maize is used in the production of various traditional foods, and its phytochemical composition has been claimed to possess health benefits. In this study, two blue maize hybrids with pigmented germ grown in five environments were studied under the hypothesis that the germ could have a different anthocyanin profile from that of anthocyanins synthesized in the aleurone layer, and that those in the germ could increase the total anthocyanin content in the whole grain. The percentage of pigmented germ, total anthocyanin content (TA) and total soluble phenols in the germ, whole grain and tortilla were evaluated to determine how tortilla color is modified.

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