Publications by authors named "C Sams"
Importance: Understanding potential predisposing factors associated with spaceflight-associated neuro-ocular syndrome (SANS) may influence its management.
Objective: To describe a severe case of SANS associated with 2 potentially predisposing factors.
Design, Setting, And Participants: Ocular testing of and blood collections from a female astronaut were completed preflight, inflight, and postflight in the setting of the International Space Station (ISS).
Darunavir is a potent HIV protease inhibitor that has been established as an effective tool in the fight against the progression of HIV/AIDS in the global community. The successful application of this drug has spurred the development of derivatives wherein strategic regions (e.g.
View Article and Find Full Text PDFBackground: Cultural humility is a lifelong commitment to self-evaluation, redressing power imbalances in patient-physician relationships and developing mutually trusting beneficial partnerships.
Objective: The objective of this study was to determine the feasibility and efficacy of cultural humility training.
Methods: From July 2020-March 2021, 90-minute educational workshops attended by 133 medical students, resident physicians and medical education faculty included 1) pre- and post- intervention surveys; 2) interactive presentation on equity and cultural humility principles; 3) participants explored sociocultural identities and power; and 4) reflective group discussions.
Article Synopsis
- Human health risk assessment traditionally relies on animal testing, guided by OECD standards, but newer methods using human-relevant in vitro models and computational approaches are proving advantageous.
- The evolution of Next Generation Risk Assessment (NGRA) emphasizes new methodologies and physiologically based kinetic (PBK) modeling, yet often overlooks the integration of human biomonitoring (HBM) data, which is key to enhancing risk assessment accuracy.
- Combining toxicokinetics, PBK models, and HBM data allows for a more comprehensive understanding of chemical exposure impacts, moving away from animal-based methods toward human-centered assessments that consider aggregate and cumulative exposures.