Publications by authors named "C Salas-Anton"
Article Synopsis
- - Cardiac amyloidosis is becoming recognized as a treatable type of heart failure, with effective therapies now available for its two common forms: immunoglobulin light chain amyloidosis and transthyretin (ATTR) amyloidosis.
- - Accurate treatment initiation depends on the proper identification of cardiac amyloidosis and the specific amyloid type, with noninvasive methods available for ATTR but histological confirmation still needed for many cases.
- - The review outlines the need for histological typing in certain patients and discusses various techniques for amyloid deposit typing, including mass spectrometry, immunohistochemistry, and immunoelectron microscopy, along with their pros and cons in clinical usage.
Introduction: We conducted a study to determine the prevalence of structural heart disease in patients with CF, the characteristics of a cardiomyopathy not previously described in this population, and its possible relationship with nutritional deficiencies in CF.
Methods: We studied 3 CMP CF patients referred for heart-lung transplantation and a prospective series of 120 adult CF patients. All patients underwent a clinical examination, blood tests including levels of vitamins and trace elements, and echocardiography with evaluation of myocardial strain.
Article Synopsis
- Whole-body autopsies of 70 COVID-19 patients were conducted to explore the disease's pathophysiology and the impact of superinfections.
- The average age of the subjects was 70, with most having pre-existing health issues; 65.71% experienced infectious complications during their hospitalization, and invasive mechanical ventilation was common.
- Key autopsy findings included severe lung damage, heart conditions, and liver issues, highlighting the significant roles of comorbidities and superinfections in COVID-19 pathology.
A 21-year-old woman with a history of atopy, peripheral eosinophilia, Wolf-Parkinson-White syndrome, and 5 episodes of myocarditis was diagnosed with eosinophilic myocarditis. Despite adequate immunosuppressive treatment and resolution of the myocarditis episode, the patient developed dilated cardiomyopathy and presented with worsening of her functional class. Finally, genetic testing unveiled an additional diagnosis: Danon disease.
View Article and Find Full Text PDFBackground: Mechanical ventilation increases the risk of lung injury (VILI). Some authors propose that the way to reduce VILI is to find the threshold of driving pressure below which VILI is minimized. In this study, we propose a method to titrate the driving pressure to pulmonary elastance in an acute respiratory distress syndrome model using Young's modulus and its consequences on ventilatory-induced lung injury.
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