Publications by authors named "C Saeki"

Frailty and fractures are closely associated with adverse clinical outcomes. This retrospective study investigated the prognostic impact of frailty, prevalent fractures, and the coexistence of both in patients with cirrhosis. Frailty was defined according to the Fried frailty phenotype criteria: weight loss, weakness, exhaustion, slowness, and low physical activity.

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  • Pareidolias are perceptual deficits where people see meaningful shapes in ambiguous visuals, studied in neurodegenerative diseases using a noise pareidolia test.
  • This research explored differences between paper-based and digital testing methods for pareidolias among healthy individuals and patients with Alzheimer's, DLB, and Parkinson's disease.
  • Results show that pareidolic perceptions remain consistent in both testing formats, and digital testing on smartphones can effectively maintain the functionality of assessing these visual illusions.
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  • Sarcopenia and osteoporosis negatively affect patients with chronic liver disease (CLD), and this study compares two methods for assessing muscle mass: bioelectrical impedance analysis (BIA) and dual-energy X-ray absorptiometry (DXA).
  • The study included 173 patients and found strong correlation and agreement between ASMI values obtained from BIA and DXA for diagnosing sarcopenia and osteosarcopenia.
  • It concludes that DXA is a valuable tool for a thorough assessment of muscle and bone health in CLD patients, highlighting the need for effective diagnostics in managing these conditions.
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  • Patients with chronic liver disease (CLD) often experience malnutrition and increased risk of bone diseases, which can lead to worse health outcomes.
  • This study included 209 CLD patients and found that those in the "nutrition-related risk" group had a higher prevalence of osteoporosis compared to those without such risk.
  • The geriatric nutritional risk index (GNRI) was determined to be a strong predictor for osteoporosis and fracture risk, indicating its potential use as an important tool for managing bone health in these patients.
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Background: Freezing of gait is one of the most disturbing motor symptoms of Parkinson's disease (PD). However, the effective connectivity between key brain hubs that are associated with the pathophysiological mechanism of freezing of gait remains elusive.

Objective: The aim of this study was to identify effective connectivity underlying freezing of gait.

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