Publications by authors named "C Sadler"
Article Synopsis
- Patients with ulcerative colitis (UC) experiencing severe flares in the hospital are a unique and high-risk group requiring specialized clinical trial designs.
- A multi-centre consortium is developing a trial for hyperbaric oxygen therapy, addressing important factors like inclusion/exclusion criteria, disease activity measures, and tailored care pathways.
- The study highlights the need for comprehensive outcome measures and standardized care practices while emphasizing the significance of early intervention and statistical planning in these small clinical trials.
Here, we present results of a computational and experimental study of adsorption of various metals on MoS. In particular, we analyzed the binding mechanism of four metallic elements (Ag, Au, Cu, Ni) on MoS. Among these elements, Ni exhibits the strongest binding and lowest mobility on the surface of MoS.
View Article and Find Full Text PDFThe global crisis of antimicrobial resistance (AMR) necessitates the development of broad-spectrum antibacterial drugs effective against multi-drug resistant (MDR) pathogens. BWC0977, a Novel Bacterial Topoisomerase Inhibitor (NBTI) selectively inhibits bacterial DNA replication via inhibition of DNA gyrase and topoisomerase IV. BWC0977 exhibited a minimum inhibitory concentration (MIC) of 0.
View Article and Find Full Text PDFIntroduction: The COVID-19 pandemic raised significant concerns about fitness to dive due to potential damage to the pulmonary and cardiovascular systems. Our group previously published guidelines (original and revised) for assessment of these divers. Here, we report a prospective, observational study to evaluate the utility of these guidelines.
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