Publications by authors named "C Sabbadin"

Papillary thyroid cancer (PTC) is the 8th most common cancer among women overall. Licorice contains over 300 active compounds, many of them with anti-cancer properties. Glycyrrhetinic acid (GA) is a major component of licorice.

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Article Synopsis
  • This text discusses a consensus on the use of inositols, particularly myo-inositol (Myo), for treating reproductive disorders in women, with a focus on those with polycystic ovary syndrome (PCOS).
  • A panel of endocrinologists and a gynecologist evaluated how Myo can help with menstrual irregularities, fertility, pregnancy outcomes, and neonatal health, resulting in eight consensus statements.
  • The findings suggest Myo can improve certain reproductive issues but highlight the need for more research to clarify its effectiveness, proper dosage, and the potential benefits of combining it with D-chiro-inositol.
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Pseudohyperaldosteronism (PHA) is characterized by hypertension, hypokalemia, and a decrease in plasma renin and aldosterone levels. It can be caused by several causes, but the most frequent is due to excess intake of licorice. The effect is mediated by the active metabolite of licorice, glycyrrhetinic acid (GA), which acts by blocking the 11-hydroxysteroid dehydrogenase type 2 and binding to the mineralocorticoid receptor (MR) as an agonist.

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