Publications by authors named "C S Stingu"
Article Synopsis
- The study focuses on the Bacteroides fragilis group (BFG), which are significant anaerobic pathogens known for their high antibiotic resistance, and aims to compare the antibiotic resistance genes in healthy individuals' microbiota with those from infected patients.
- Researchers found 13 antibiotic resistance determinants in 184 intestinal BFG strains collected from five European countries, revealing differences in gene prevalence compared to previous studies, particularly in mobile antibiotic resistance genes.
- The findings suggest novel characteristics in intestinal Bacteroides strains, indicating differing prevalence of resistance genes based on their microbiota composition and offering insights into their resistance mechanisms.
Denture prostheses are an ideal and extensive reservoir for microorganisms to attach to their surfaces. The aim of the study was to elucidate interactions between materials for the fabrication of denture bases and the attachment of microorganisms, focusing on respiratory pathogens and species. Specimens (6 mm × 1 mm) with a standardized surface roughness (Sa = 0.
View Article and Find Full Text PDFThe phenotypic expression of antibiotic resistance genes (ARGs) can hamper the use of antibiotics as adjuncts to subgingival instrumentation in the treatment of periodontitis patients. The aim of the study was to analyze the relationship between the phenotypic and genotypic resistance against ampicillin-sulbactam, clindamycin, doxycycline and metronidazole of subgingival biofilm samples from 19 periodontitis patients. Samples were analyzed with shotgun sequencing and cultivated anaerobically for 7 days on microbiological culture media incorporating antibiotics.
View Article and Find Full Text PDFAnaerobes play an important role in clinically relevant infections and resistance is increasing worldwide. We tested 120 rare anaerobic isolates belonging to 16 genera for antimicrobial resistance using the agar dilution method and compared those results to the time-saving E-test method. The susceptibility data for 12 antimicrobial substances (benzylpenicillin, ampicillin/sulbactam, piperacillin/tazobactam, imipenem, meropenem, cefoxitin, metronidazole, moxifloxacin, clindamycin, doxycycline, tigecycline, eravacycline) were collected.
View Article and Find Full Text PDFBackground: Rectal swabs are well-implemented screening tools for multidrug-resistant bacteria (MDRB). Since certified swabs such as the Copan eSwab system experienced a delivery bottleneck during the COVID-19 pandemic, commercially available alternatives such as commonly used double-tipped cotton swabs had to be investigated, especially considering their similarity to professional cotton swabs for microbiological purposes.
Methods: Diagnostic properties of commercial cotton swabs (comparable to Q-tips) and Copan eSwabs were qualitatively compared in a prospective single-center study using microbiological standard cultures and PCR methods for the detection of multidrug-resistant Gram-negative bacteria and vancomycin-resistant enterococci (VRE).