Ultraviolet radiation, both UVA and UVB, influences the composition of the skin microbiome.

Background: Studies have begun to investigate the complex relationship between host and microorganisms in non-infectious pathologies such as acne, atopic dermatitis and psoriasis. Though the skin is exposed to environmental stressors such as ultraviolet radiation (UVR), no studies exist examining the effects of both UVA and UVB on the skin microbiome.

Objective: To test the effect of UVA and UVB on human skin microbiome.

Shape, shell, and vacuole formation during the drying of a single concentrated whey protein droplet.

The drying of milk concentrate droplets usually leads to specific particle morphology influencing their properties and their functionality. Understanding how the final shape of the particle is formed therefore represents a key issue for industrial applications. In this study, a new approach to the investigation of droplet-particle conversion is proposed.

Conjugation of synthetic N-acetyl-lactosamine to azide-containing proteins using the Staudinger ligation.

Generation of defined glycoconjugates is necessary for the study of glycoprotein function, as well as the development of therapeutics. The biosynthesis of glycoproteins produces multiple glycoforms, proteins which differ only in the structure of the attached glycan. This inherent heterogeneity complicates the study of isolated glycans and, in particular, could obscure the role of individual glycan epitopes in biological function.

Fluorescent small-molecule probes of biochemistry at the plasma membrane.

The function of cellular membranes remains a critical area of study. Advances in molecular biology and biochemistry have helped to define the plasma membrane as a dynamic and heterogeneous structure. Probes capable of resolving molecular interactions and biochemical changes within the membrane are becoming a necessary tool for cell biology studies.

Protein tyrosine phosphatase hPTPN20a is targeted to sites of actin polymerization.

The human genome encodes 38 classical tyrosine-specific PTPs (protein tyrosine phosphatases). Many PTPs have been shown to regulate fundamental cellular processes and several are mutated in human diseases. We report that the product of the PTPN20 gene at the chromosome locus 10q11.