Development of a panchromatic acrylamide-based photopolymer for multicolor reflection holography.

We present the development of a panchromatic acrylamide-based photopolymer (ABP) for holographic recording application. The scattering of the recording medium was characterized by measuring the bidirectional scattering distribution function. The dynamic range in the reflection mode of recording was evaluated by measuring the diffraction efficiencies of the holographic gratings recorded individually at 633 nm, 532 nm, and 473 nm wavelengths at spatial frequencies of 4200 lines/mm, 5000 lines/mm, and 5700 lines/mm, respectively.

Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects.

OBJECTIVE- Tall-like receptor (TLR)4 has been implicated in the pathogenesis of free fatty acid (FFA)-induced insulin resistance by activating inflammatory pathways, including inhibitor of kappaB (IkappaB)/nuclear factor kappaB (NFkappaB). However, it is not known whether insulin-resistant subjects have abnormal TLR4 signaling. We examined whether insulin-resistant subjects have abnormal TLR4 expression and TLR4-driven (IkappaB/NFkappaB) signaling in skeletal muscle.

Adiponectin, a fat cell product, influences the earliest lymphocyte precursors in bone marrow cultures by activation of the cyclooxygenase-prostaglandin pathway in stromal cells.

Adiponectin, an adipocyte-derived hormone, is attracting considerable interest as a potential drug for diabetes and obesity. Originally cloned from human s.c.

Regulation of endometrial granulocyte macrophage-colony stimulating factor (GM-CSF) in the ewe.

Granulocyte macrophage-colony stimulating factor (GM-CSF) increases ovine interferon-tau (oIFNtau) secretion by ovine conceptuses, but endometrial production of GM-CSF has not been characterized. Endometrial GM-CSF expression was evaluated in ovariectomized ewes implanted with estradiol-17beta (E(2)) and/or progesterone (P(4)) for 14 days, in day 14 cyclic and day 14 pregnant ewes. Relative levels of endometrial GM-CSF mRNA were 3-fold higher in E(2)- and E(2)/P(4)-treated ewes than that of control or P(4)-treated ovariectomized ewes.

Paracrine regulation of fat cell formation in bone marrow cultures via adiponectin and prostaglandins.

Adiponectin, an adipocyte-derived hormone, was recently shown to have potential therapeutic applications in diabetes and obesity because of its influence on glucose and lipid metabolism. We found that brown fat in normal human bone marrow contains this protein and used marrow-derived preadipocyte lines and long-term cultures to explore potential roles in hematopoiesis. Recombinant adiponectin blocked fat cell formation in long-term bone marrow cultures and inhibited the differentiation of cloned stromal preadipocytes.