Specialist pharmacist prescribing in dermatology.

Across the country, pharmacists are developing their professional competencies to move outside the dispensary and directly integrate with specialist teams. Within dermatology, the widespread use of high-cost and high-risk pharmacological interventions presents a range of opportunities for a pharmacist to contribute to safer, more cost-effective use of medicines. As well as using prescribing qualifications to take on clinical workloads, pharmacists can enact cost-saving changes to routine prescribing; improve clinical governance and use their expertise in medicines to effectively advocate for access to new or alternative treatment options, as well as demystify complex funding pathways.

Identifying internal and external shoulder rotation using a kirigami-based shoulder patch.

Internal and external rotation of the shoulder is often challenging to quantify in the clinic. Existing technologies, such as motion capture, can be expensive or require significant time to setup, collect data, and process and analyze the data. Other methods may rely on surveys or analog tools, which are subject to interpretation.

The Effects of Percentage-Based, Rating of Perceived Exertion, Repetitions in Reserve, and Velocity-Based Training on Performance and Fatigue Responses.

Cowley, N, Nicholson, V, Timmins, R, Munteanu, G, Wood, T, García-Ramos, A, Owen, C, and Weakley, J. The effects of percentage-based, rating of perceived exertion, repetitions in reserve, and velocity-based training on performance and fatigue responses. J Strength Cond Res XX(X): 000-000, 2024-This study assessed the effects of percentage-based training (%1RM), rating of perceived exertion (RPE), repetitions in reserve (RIR), and velocity-based training (VBT) on (a) acute kinematic outputs, perceptions of effort, and changes in neuromuscular function during resistance training; and (b) neuromuscular fatigue and perceptions of soreness 24 hours after exercise.

TracMyAir smartphone application for modeling exposures to PM and ozone - Integration with air quality networks and location-activity sensors.

Epidemiologic studies of ambient fine particulate matter (PM) and ozone (O) often use outdoor concentrations from central-site monitors or air quality model estimates as exposure surrogates, which can result in exposure errors. We previously developed an exposure model called TracMyAir, which is an iPhone application that determines seven tiers of individual-level exposure metrics for ambient PM and O using outdoor concentrations, home building characteristics, weather, time-activities. The exposure metrics with increasing information needs and complexity include: outdoor concentration (C, Tier 1), building infiltration factor (F, Tier 2), indoor concentration (C, Tier 3), time spent in microenvironments (ME) (T, Tier 4), personal exposure factor (F, Tier 5), exposure (E, Tier 6), and inhaled dose (D, Tier 7).

Underrepresentation of Small Lymphocytic Lymphoma in Clinical Trials for Chronic Lymphocytic Leukemia.

Background: Although chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are the same biologic disease entity and warrant identical treatment approaches, patients with SLL have frequently been excluded from clinical trials in CLL.

Methods: This study assessed the representation of patients with SLL among Phase II or III clinical trials cited in the 2024 National Comprehensive Cancer Network (NCCN) treatment guidelines.

Results: Patients with SLL were explicitly eligible for only 21 (38%) of the 56 clinical trials for CLL, comprising 222 (6%) of the 3440 enrolled patients.