Publications by authors named "C S Malcolm"

Objectives: This study aimed to conduct an epidemiological and genomic investigation of a hospital outbreak of , and implement measures for its control.

Methods: We collected demographic and clinical data from medical records of patients with from January 2017 to June 2019 after identifying increased cases in April 2019. Point-prevalence surveys for colonisation were conducted in the critical care units (CCU).

View Article and Find Full Text PDF

Spatial navigation is a multi-faceted behaviour drawing on many different aspects of cognition. Visuospatial abilities, such as mental rotation and visuospatial working memory, in particular, may be key factors. A range of tests have been developed to assess visuospatial processing and memory, but how such tests relate to navigation ability remains unclear.

View Article and Find Full Text PDF
Article Synopsis
  • About 25% of people worldwide have non-alcoholic fatty liver disease (NAFLD), but there are no specific medications to treat it currently.
  • This study focused on the adiposity-associated receptor GPR75, mainly found in the brain, and its role in reducing fat accumulation in the liver.
  • Mice lacking GPR75 were able to control their food intake better on a high-fat diet, which also correlated with human genetic data showing that certain GPR75 variants lower the risk of developing liver fat, highlighting its potential as a target for NAFLD therapy.
View Article and Find Full Text PDF

Objective: To inform interventions focused on safely reducing urgent paediatric short stay admissions (SSAs) for convulsions.

Methods: Routinely acquired administrative data from hospital admissions in Scotland between 2015-2017 investigated characteristics of unscheduled SSAs (an urgent admission where admission and discharge occur on the same day) for a diagnosis of febrile and/or afebrile convulsions. Semi-structured interviews to explore perspectives of health professionals (n = 19) making referral or admission decisions about convulsions were undertaken.

View Article and Find Full Text PDF

Assessment practices in Higher Education remain beholden to the twin pillars of neoliberal economic orthodoxy and White supremacy. The former has given rise to the modularization and commodification of education, wherein student performance is measured according to narrow and often meaningless metrics that foster and maintain ineffective assessment mechanisms. The latter imbues those metrics with a deference to, and valorization of, "Whiteness" as a marker of success, and this manifests in persistent awarding gaps across the sector.

View Article and Find Full Text PDF