Double peak sign on ultrasonography: A new prognostic marker before surgery for white cataract.

A mature, hypermature, or white cataract needs posterior segment evaluation before surgery for prognostification. Ultrasonography is the preferred method for this. White cataract or intumescent cataract risks intraoperative capsulorhexis running out leading to devastating complications due to high intralenticular pressure.

Plant Derived Immunomodulators; A Critical Review.

The concept of immunomodulation was proposed by Edward Jenner, while working on polio vaccine in 1796. Many of the autoimmune diseases such as rheumatoid arthritis, inflammatory bowel diseases, psoriatic arthritis and system lupus erythematosus, viral diseases and, some cancers are characterized with elevated levels of "immunocytokine" gene expression, including, tumor necrosis factor-α, various interleukins, cytotoxic T-cell antigen-4, B-cell activating factor. For the treatment of these diseases, the immunologically-based therapies play the major role.

A holistic review on Cryptococcus neoformans.

Cryptococcus neoformans is an encapsulated fungal pathogen that causes infection in immunocompromised individuals such as HIV patients, organ transplant patients, hematological malignancies, diabetes patients, etc. The most common invasive fungal pathogens are Candida spp., Aspergillus spp.

Expression of survivin in oral leukoplakia and oral lichen planus.

Background: Up to one third (3-33%) oral squamous cell carcinomas develop from potentially malignant lesions. Most common potentially malignant lesions (PML) are leukoplakia and lichen planus. It is very important to diagnose PML at early stage to prevent malignant transformation of lesion.