Reduced Concussion Symptom Burden in Early Adolescent Athletes Using a Head-Neck Cooling Device.

Objective: To determine whether an investigational head-neck cooling device, Pro2cool, can better reduce symptom severity compared with standard postconcussion care in early adolescent athletes after a sports-related concussion.

Design: Prospective, longitudinal, randomized trial design conducted over a 28-day period.

Setting: Six pediatric medical centers in Ohio and Michigan.

Supercontinuum generation in single-crystal YAG fibers pumped around the zero-dispersion wavelength.

Yttrium aluminum garnet (YAG) is a common host material for both bulk and single-crystal fiber lasers. With increasing interest in developing optical technologies in the short-wave infrared and mid-infrared wavelength range, YAG may be a potential supercontinuum medium for these applications. Here, we characterize femtosecond laser pumped supercontinuum generation with 1200-2000 nm pump wavelengths () for undoped, single-crystal YAG fibers, which are representative of the normal, zero, and anomalous-dispersion regimes.

Preliminary Safety and Efficacy of Head and Neck Cooling Therapy After Concussion in Adolescent Athletes: A Randomized Pilot Trial.

Objective: To determine the safety and efficacy of head and neck cooling when applied up to 8 days after concussion among adolescent athletes.

Design: A randomized nonblinded pilot trial.

Setting: Sports Medicine Clinic in a tertiary hospital.

Single-Shot Multi-Stage Damage and Ablation of Silicon by Femtosecond Mid-infrared Laser Pulses.

Although ultrafast laser materials processing has advanced at a breakneck pace over the last two decades, most applications have been developed with laser pulses at near-IR or visible wavelengths. Recent progress in mid-infrared (MIR) femtosecond laser source development may create novel capabilities for material processing. This is because, at high intensities required for such processing, wavelength tuning to longer wavelengths opens the pathway to a special regime of laser-solid interactions.

A Versatile Optical Clearing Protocol for Deep Tissue Imaging of Fluorescent Proteins in Arabidopsis thaliana.

Confocal microscopy is widely used to visualize gene expression patterns and developmental processes in plants. However, the imaging of plant tissue can be challenging due to its opacity, which often makes previous immersion in a clearing agent necessary. Many commonly-used chemicals suffer either from their incompatibility with fluorescent proteins or their complex and lengthy application.