Publications by authors named "C S Ejezie"
Background: Rifampicin, an antibiotic used in the treatment of tuberculosis has raised concerns about its potential liver and kidney toxicity.
Aim: This study aimed to evaluate the protective effects of Aloe vera against hepatorenal toxicity induced by rifampicin in male Wistar rats.
Methods: Thirty rats were divided into six groups (n = 5): group A (control), group B treated with rifampicin, groups C-E treated with varying doses (50, 100, and 200 mg/kg) of Aloe vera alongside rifampicin as well as a group F treated with furosemide and rifampicin for a total of 30 days.
Background: Selinexor (SEL) is a nuclear exportin 1 inhibitor that blocks the transport of nuclear proteins, including tumor suppressors, to the cytoplasm. Preclinical data suggest that the combination of SEL with checkpoint blockade may result in improved response to immunotherapy.
Methods: NCT02419495 was a multiarm phase IB study of SEL in combination with other standard regimens in patients with advanced malignancies.
Background: The use of digital health strategies for cancer care increased dramatically in the United States over the past 4 years. However, a dearth of knowledge remains about the use of digital health for cancer prevention for some populations with heath disparities. Therefore, the purpose of the present scoping review was to identify digital health interventions for cancer prevention designed for people with disabilities.
View Article and Find Full Text PDFBackground: Considerable morbidity is attributable to inappropriate tracheal cuff pressure. An earlier study undertaken in our hospital revealed that a normal cuff pressure of 20-30 cm HO was achieved in only 6% of intubated patients using subjective estimation methods.
Objective: To determine whether a training intervention could improve the accuracy of the subjective estimation method in our tracheal cuff monitoring.