Publications by authors named "C S E Bulte"
Autism spectrum disorders (ASD) have a complex pathogenesis thought to include both genetic and extrinsic factors. Among the latter, inflammation of the developing brain has recently gained growing attention. However, how genetic predisposition and inflammation might converge to precipitate autistic behavior remains elusive.
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- Endothelial disorders leading to edema and poor tissue oxygenation are common in cardiac surgery with CPB, prompting researchers to investigate the protective effects of albumin as a component in the CPB circuit.
- In a study with male rats, CPB primed with LR/albumin/mannitol resulted in lower pulmonary edema compared to 6% hydroxyethyl starch (HES) despite similar renal edema levels, indicating potential benefits of using albumin in surgical settings.
- Although microcirculatory perfusion was impaired during CPB for both groups and did not improve post-CPB, the LR/albumin/mannitol group needed significantly less fluid and medication to maintain adequate blood flow, alongside showing reduced inflammatory markers
Encouraging routine COVID-19 vaccinations is likely to be a crucial policy challenge for decades to come. To avert hundreds of thousands of unnecessary hospitalizations and deaths, adoption will need to be higher than it was in the autumn of 2022 or 2023, when less than one-fifth of Americans received booster vaccines. One approach to encouraging vaccination is to eliminate the friction of transportation hurdles.
View Article and Find Full Text PDFSevere traumatic brain injury (TBI) is a frequent cause of morbidity and mortality worldwide. In the Netherlands, suspected TBI is a criterion for the dispatch of the physician-staffed helicopter emergency medical services (HEMS) which are operational 24 h per day. It is unknown if patient outcome is influenced by the time of day during which the incident occurs.
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