Publications by authors named "C S Brian Chia"
Background: Fungating breast wounds cause significant complications and morbidity to patients. Wound care is of paramount importance in optimising care and alleviating suffering for patients with malignant breast wounds. Currently, routinely implemented objective assessment tools for fungating breast wound treatment outcomes are non-existent, and institutional practice varies.
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- * The study aims to explore if combining standard exercises with pulse electromagnetic field therapy can enhance stability and reduce muscle weakness in patients with chronic ankle instability.
- * A randomized trial with 48 participants will compare the effects of active therapy with a placebo over 8 weeks, with evaluations conducted at multiple follow-up points.
Background: Prehabilitation has been increasingly utilized to optimize perioperative outcomes. In this study, we aim to evaluate the impact of uni- and multimodal prehabilitation on functional capacity and postoperative outcomes among surgical oncology patients undergoing major abdominal surgery.
Patients And Methods: Three electronic databases (PubMed, Embase, Cochrane) were systematically searched up until December 2023.
Insulin resistance, stem cell dysfunction, and muscle fiber dystrophy are all age-related events in skeletal muscle (SKM). However, age-related changes in insulin isoforms and insulin receptors in myogenic progenitor satellite cells have not been studied. Since SKM is an extra-pancreatic tissue that does not express mature insulin, we investigated the levels of insulin receptors (INSRs) and a novel human insulin upstream open reading frame (INSU) at the mRNA, protein, and anatomical levels in Baltimore Longitudinal Study of Aging (BLSA) biopsied SKM samples of 27-89-year-old (yrs) participants.
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