Publications by authors named "C Rumpel"
Article Synopsis
- Mangroves are vital for carbon storage but are threatened by human activities.
- Iron oxides play a crucial role in stabilizing soil organic carbon (SOC), especially poorly crystalline forms that better protect SOC from degradation.
- Land use changes, like converting mangroves to pastures and shrimp ponds, significantly reduce the capacity of iron to retain SOC, impacting carbon sequestration.
Article Synopsis
- Plastic pollution is widespread, even in agricultural soils that receive urban compost, posing risks to the environment and health.
- This study aimed to explore how coarse microplastics accumulate in soil over time when using different types of urban compost, analyzing samples from a 21-year experiment.
- Results showed that the compost type influenced the amount of microplastics in the soil, revealing that while the number of particles was consistent with estimates, the mass measurements varied, potentially due to processes like biological transport or physical breakdown.
Objective: Vestibular schwannomas (VS), benign tumors stemming from the eighth cranial nerve's Schwann cells, are associated with Merlin gene mutations, inflammation, and the tumor microenvironment (TME), influencing tumor initiation, maintenance, and potential neural dysfunction. Understanding TME composition holds promise for systemic therapeutic interventions, particularly for NF2-related schwannomatosis.
Methodology: A retrospective analysis of paraffin-embedded tissue from 40 patients (2013-2020), evenly divided by neurofibromatosis type 2 status, with further stratification based on magnetic resonance imaging (MRI) progression and hearing function.
Background: Our goal was to develop a 3D tumor slice model, replicating the individual tumor microenvironment and for individual pharmaceutical testing in vestibular schwannomas with and without relation to NF2.
Methods: Tissue samples from 16 VS patients (14 sporadic, 2 NF2-related) were prospectively analyzed. Slices of 350 µm thickness were cultured in vitro, and the 3D tumor slice model underwent thorough evaluation for culturing time, microenvironment characteristics, morphology, apoptosis, and proliferation rates.